LMO2 抗体 (AA 1-159)
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Quick Overview for LMO2 抗体 (AA 1-159) (ABIN7868222)
抗原
See all LMO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-159
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原理
- Danre Lmo2 Antibody / Rhombotin 2
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived Danre Lmo2 recombinant protein (amino acids M1-V159) was used as the immunogen for the Danre Lmo2 antibody.
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亚型
- Ig Fraction
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anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 23-140) antibody
LMO2 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal LMO2-1971 unconjugated
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibodyLMO2 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4D8 unconjugated
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibodyLMO2 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-158) antibodyLMO2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B8 unconjugated
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 23-140) antibodyLMO2 适用: 人 WB, IHC, FACS 宿主: 小鼠 Monoclonal rLMO2-1971 unconjugated Recombinant Antibody
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 23-140) antibodyLMO2 适用: 人 WB, FACS, IF 宿主: 兔 Monoclonal LMO2-3147R unconjugated Recombinant Antibody
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-100) antibodyLMO2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-30), (N-Term) antibodyLMO2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33753 unconjugated
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) (AA 1-30) antibodyLMO2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Only 2 (Rhombotin-Like 1) (LMO2) antibodyLMO2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Danre Lmo2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Danre Lmo2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
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别名
- Lmo2
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背景
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Lmo2, or LIM domain only protein two, is a transcriptional regulator that plays a critical role in hematopoietic and vascular development. In zebrafish, Lmo2 is essential for the specification of blood and endothelial lineages and is widely used as a molecular marker for early hematopoietic progenitor cells.
Lmo2 does not directly bind to DNA but functions as a scaffold protein, forming complexes with other transcription factors to regulate gene expression. During zebrafish embryogenesis, Lmo2 is expressed in the intermediate cell mass, the site of primitive blood cell formation, and in the developing vasculature. It is required for the emergence of both erythroid and myeloid lineages, as well as for the proper development of endothelial cells.
Loss of Lmo2 function in zebrafish results in severe defects in blood cell formation and vascular patterning, highlighting its central role in mesodermal differentiation. Because of its strong evolutionary conservation and defined expression patterns, zebrafish Lmo2 serves as a powerful model for studying hematopoiesis, angiogenesis, and transcriptional networks involved in early development.
Lmo2 is also relevant to human health, as misregulation of Lmo2 has been associated with leukemia. This makes zebrafish Lmo2 a valuable tool in both basic research and disease modeling related to blood development and cancer biology.
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UniProt
- Q9PTJ3
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途径
- Chromatin Binding
抗原
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