PEG3 抗体 (AA 1-1548)
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Quick Overview for PEG3 抗体 (AA 1-1548) (ABIN7868215)
抗原
See all PEG3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-1548
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原理
- PEG3 Antibody / Paternally-expressed gene 3
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids M1-R1548) was used as the immunogen for the PEG3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PEG3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PEG3 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PEG3 (Paternally Expressed 3 (PEG3))
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别名
- PEG3
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背景
- Paternally-expressed gene 3 protein is a protein that in humans is encoded by the PEG3 gene. In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
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UniProt
- Q9GZU2
抗原
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