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Recombinant IL-15 抗体 (AA 1-152)

The 小鼠 单克隆 anti-IL-15 antibody (Clone rIL15-8049) (ABIN7868194) specifically detects IL-15 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7868194
发货至: 中国
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Quick Overview for Recombinant IL-15 抗体 (AA 1-152) (ABIN7868194)

抗原

See all IL-15 (IL15) 抗体
IL-15 (IL15) (Interleukin 15 (IL15))

抗体类型

Recombinant Antibody

适用

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宿主

  • 94
  • 60
  • 7
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  • 1
小鼠

克隆类型

  • 93
  • 76
单克隆

标记

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This IL-15 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RIL15-8049
  • 抗原表位

    • 42
    • 7
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    AA 1-152

    原理

    Interleukin-15 Antibody / IL15

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-152) from the human protein was used as the immunogen for the Interleukin-15 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Interleukin-15 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Interleukin-15 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-15 (IL15) (Interleukin 15 (IL15))

    别名

    Interleukin-15

    背景

    Interleukin-15 (IL-15), also designated IL-T, is a cloned cytokine which shares several biological activities but no sequence homology with IL-2. Human, mouse and simian IL-15 cDNA clones have been isolated and characterized. All 3 species encode a 162 amino acid residue precursor protein containing a 48 amino acid leader that is cleaved to generate the mature form of IL-15. IL-15 stimulates the proliferation of T cells and NK cells, while enhancing B cell expansion and antibody production. Unlike IL-2, IL-15 is not produced by lymphocytes, but appears to be produced by macrophages, epithelial lines, muscle and placenta. IL-15 has also been shown to be a chemoattractant for human blood T lymphocytes and to be able to induce lymphokine-activated killer (LAK) activity in NK cells as well as to be able to induce the generation of cytolytic effector cells. Studies have shown that IL-15 is the only other cytokine that shares the beta signaling subunit of the IL-2R. Evidence also suggests that like IL-2, IL-4 and IL-7, IL-15 utilizes the common IL-2Rgamma subunit.

    UniProt

    P40933

    途径

    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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