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Iba1 抗体 (AA 1-146)

The 小鼠 单克隆 anti-Iba1 antibody (Clone AIF1-2493) (ABIN7868167) specifically detects Iba1 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7868167
发货至: 中国
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Quick Overview for Iba1 抗体 (AA 1-146) (ABIN7868167)

抗原

See all Iba1 (IBA1) 抗体
Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

适用

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宿主

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小鼠

克隆类型

  • 102
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单克隆

标记

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This Iba1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

AIF1-2493
  • 抗原表位

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    AA 1-146

    原理

    AIF1 Antibody / IBA1

    纯化方法

    Protein G affinity chromatography

    免疫原

    A portion of amino acids 1-146 from the human protein was used as the immunogen for the AIF1 antibody.

    亚型

    IgG2c, kappa
  • 应用备注

    Titering of the AIF1 antibody may be required for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the AIF1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

    别名

    AIF1

    背景

    AIF1 (Allograft inflammatory factor 1), also called IBA1 (Ionized calcium-binding adapter molecule 1) is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1/IBA1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, it colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding the protein resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

    UniProt

    P55008

    途径

    Smooth Muscle Cell Migration
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