Iba1 抗体 (AA 1-146)
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Quick Overview for Iba1 抗体 (AA 1-146) (ABIN7868164)
抗原
See all Iba1 (IBA1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-146
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原理
- IBA1 Antibody / AIF1 (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 1-146 from the human protein was used as the immunogen for the IBA1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Titering of the IBA1 antibody may be required for optimal performance.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the IBA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
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别名
- IBA1
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背景
- AIF1 (Allograft inflammatory factor 1), also called IBA1 (Ionized calcium-binding adapter molecule 1) is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1/IBA1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, it colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding the protein resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
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UniProt
- P55008
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途径
- Smooth Muscle Cell Migration
抗原
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