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Recombinant Iba1 抗体 (AA 1-146)

This 小鼠 单克隆 antibody specifically detects Iba1 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7868162
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Recombinant Iba1 抗体 (AA 1-146) (ABIN7868162)

抗原

See all Iba1 (IBA1) 抗体
Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

抗体类型

Recombinant Antibody

适用

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宿主

  • 125
  • 60
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  • 1
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小鼠

克隆类型

  • 102
  • 91
单克隆

标记

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  • 11
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  • 1
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  • 1
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This Iba1 antibody is un-conjugated

应用范围

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  • 27
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  • 14
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RAIF1-1909
  • 抗原表位

    • 42
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    AA 1-146

    原理

    Recombinant IBA1 Antibody / AIF1 (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A portion of amino acids 1-146 from the human protein was used as the immunogen for the recombinant IBA1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Titering of the recombinant IBA1 antibody may be required for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant IBA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

    别名

    IBA1

    背景

    AIF1 (Allograft inflammatory factor 1), also called IBA1 (Ionized calcium-binding adapter molecule 1) is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1/IBA1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, it colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding the protein resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

    UniProt

    P55008

    途径

    Smooth Muscle Cell Migration
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