SIVA1 抗体 (AA 1-141)
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Quick Overview for SIVA1 抗体 (AA 1-141) (ABIN7868145)
抗原
See all SIVA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-141
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原理
- SIVA1 Antibody / CD27BP
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids M1-T141) was used as the immunogen for the SIVA1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SIVA1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SIVA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
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别名
- SIVA1
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背景
- Apoptosis regulatory protein Siva is a protein that in humans is encoded by the SIVA1 gene. This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis.
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UniProt
- O15304
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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