CLPS 抗体 (AA 1-112)
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Quick Overview for CLPS 抗体 (AA 1-112) (ABIN7867958)
抗原
See all CLPS 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-112
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原理
- CLPS Antibody / Colipase (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment (within amino acids 1-112) of human Colipase protein was used as the immunogen for the CLPS antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the CLPS antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the CLPS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CLPS (Colipase, Pancreatic (CLPS))
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别名
- CLPS
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背景
- The lipase gene family belongs to one of the most robust genetic superfamilies found in living organisms, which includes esterases and thioesterases. Members of the AB hydrolase subfamily include Hepatic Lipase (HL), Endothelial Lipase (EL), Lipoprotein Lipase (LPL), Pancreatic Lipase (PL), Gastric Lipase (GL) and LCAT. These family members play a crucial role in the metabolism of lipids. Pancreatic lipase, also designated pancreatic triacylglycerol acyl hydrolase, is important for dietary fat absorption as it hydrolyses triglycerides into diglycerides, monoglycerides and free fatty acids. Colipase, also known as CLPS or pancreatic colipase preproprotein, is a 112 amino acid secreted protein that functions as a cofactor of pancreatic lipase. Necessary for dietary lipid hydrolysis and localizing to pancreatic acinar cells, colipase allows pancreatic lipase to anchor itself to the lipid-water interface of lipid micelles, thereby preventing intestinal bile salts from washing it off.
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UniProt
- P04118
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途径
- Lipid Metabolism
抗原
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