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alpha KGDHC 抗体 (AA 1-1023)

The 兔 多克隆 anti-alpha KGDHC antibody (ABIN7867921) specifically detects alpha KGDHC in WB, ELISA 和 FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7867921
发货至: 中国
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Quick Overview for alpha KGDHC 抗体 (AA 1-1023) (ABIN7867921)

抗原

See all alpha KGDHC (alphaKGDHC) 抗体
alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 26
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多克隆

标记

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This alpha KGDHC antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-1023

    原理

    OGDH Antibody / 2-oxoglutarate dehydrogenase

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids M1-S1023) was used as the immunogen for the OGDH antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the OGDH antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the OGDH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))

    别名

    OGDH

    背景

    Alpha-ketoglutarate dehydrogenase also known as 2-oxoglutarate dehydrogenase E1 component, mitochondrial is an enzyme that in humans is encoded by the OGDH gene. This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[

    UniProt

    Q02218
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