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Recombinant Gastrin 抗体 (AA 1-101)

The 兔 单克隆 anti-Gastrin antibody is suitable to detect Gastrin in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7867908
发货至: 中国
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Quick Overview for Recombinant Gastrin 抗体 (AA 1-101) (ABIN7867908)

抗原

See all Gastrin (GAST) 抗体
Gastrin (GAST)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 71
  • 50
单克隆

标记

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This Gastrin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

GAST-8646R
  • 抗原表位

    • 15
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    AA 1-101

    原理

    Recombinant Gastrin Antibody

    纯化方法

    Protein A affinity

    免疫原

    A portion of amino acids 1-101 from human GAST protein was used as the immunogen for the recombinant Gastrin antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant Gastrin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant Gastrin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Gastrin (GAST)

    别名

    Gastrin

    背景

    Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems.

    UniProt

    P01350
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