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Recombinant WT1 抗体 (AA 1-100)

This 小鼠 单克隆 antibody specifically detects WT1 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7867898
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Recombinant WT1 抗体 (AA 1-100) (ABIN7867898)

抗原

See all WT1 抗体
WT1 (Wilms Tumor 1 (WT1))

抗体类型

Recombinant Antibody

适用

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宿主

  • 113
  • 85
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小鼠

克隆类型

  • 126
  • 73
单克隆

标记

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This WT1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RWT1-6908
  • 抗原表位

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    AA 1-100

    原理

    Recombinant WT1 Antibody / Wilms Tumor 1

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 1-100 was used as the immunogen for the recombinant WT1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the recombinant WT1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant WT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    WT1 (Wilms Tumor 1 (WT1))

    别名

    WT1

    背景

    The WT1 gene located at chromosome 11p13 codes for a transcription factor, a DNA-binding nucleoprotein, that plays a role primarily in the development of genitourinary organs. There are at least eight isoforms ranging between 52 and 62 kDa produced by a combination of alternative splicing and RNA editing. WT1 is synthesized and reside in the cytoplasm in an inactive form. When activated through phosphorylation it is translocated to the nucleus. In tumor tissues, WT1 is detected in tumor cells of Wilms Tumor (also known as nephroblastoma) and mesothelioma. Additionally, WT1 expression has been found in ovarian serous carcinomas and some breast carcinomas. WT1 is particularly used for distinguishing malignant mesothelioma and ovarian serous carcinoma from non-serous carcinomas.

    UniProt

    P19544

    途径

    Tube Formation
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