Recombinant WT1 抗体 (AA 1-100)
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北京 101111
Quick Overview for Recombinant WT1 抗体 (AA 1-100) (ABIN7867898)
抗原
See all WT1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-100
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原理
- Recombinant WT1 Antibody / Wilms Tumor 1
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 1-100 was used as the immunogen for the recombinant WT1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the recombinant WT1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant WT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- WT1 (Wilms Tumor 1 (WT1))
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别名
- WT1
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背景
- The WT1 gene located at chromosome 11p13 codes for a transcription factor, a DNA-binding nucleoprotein, that plays a role primarily in the development of genitourinary organs. There are at least eight isoforms ranging between 52 and 62 kDa produced by a combination of alternative splicing and RNA editing. WT1 is synthesized and reside in the cytoplasm in an inactive form. When activated through phosphorylation it is translocated to the nucleus. In tumor tissues, WT1 is detected in tumor cells of Wilms Tumor (also known as nephroblastoma) and mesothelioma. Additionally, WT1 expression has been found in ovarian serous carcinomas and some breast carcinomas. WT1 is particularly used for distinguishing malignant mesothelioma and ovarian serous carcinoma from non-serous carcinomas.
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UniProt
- P19544
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途径
- Tube Formation
抗原
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