Recombinant HBA1 抗体 (AA 1-100)
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Quick Overview for Recombinant HBA1 抗体 (AA 1-100) (ABIN7867859)
抗原
See all HBA1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-100
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原理
- Recombinant Hemoglobin alpha Antibody / HBA (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment (within amino acids 1-100) of human HBA2 protein was used as the immunogen for the recombinant Hemoglobin alpha antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the recombinant Hemoglobin alpha antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant Hemoglobin alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- HBA1 (Hemoglobin, alpha 1 (HBA1))
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别名
- Hemoglobin alpha
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背景
- Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The alpha and beta globin loci determine the basic Hgb structure. The globin portion of Hgb consists of two alpha chains and two beta chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between alpha and beta chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the alpha1-beta2 cleavage plane. When the two alpha1-beta2 interfaces are closely bound, Hgb has a low affinity for oxygen. Hb A, which contains two alpha chains plus two beta chains, comprises 97 % of total circulating hemoglobin. The remaining 3 % of total circulating hemoglobin is comprised of Hb A-2, which consists of two alpha chains plus two delta chains, and fetal hemoglobin (Hb F), which consists of two alpha chains together with two gamma chains.
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UniProt
- P69905
抗原
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