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Recombinant HBA1 抗体 (AA 1-100)

This 兔 单克隆 antibody specifically detects HBA1 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7867859
发货至: 中国
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Quick Overview for Recombinant HBA1 抗体 (AA 1-100) (ABIN7867859)

抗原

See all HBA1 抗体
HBA1 (Hemoglobin, alpha 1 (HBA1))

抗体类型

Recombinant Antibody

适用

  • 56
  • 31
  • 15
  • 2
  • 2

宿主

  • 58
  • 9

克隆类型

  • 41
  • 26
单克隆

标记

  • 39
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This HBA1 antibody is un-conjugated

应用范围

  • 42
  • 32
  • 18
  • 17
  • 12
  • 8
  • 7
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

HBA-9193R
  • 抗原表位

    • 14
    • 8
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-100

    原理

    Recombinant Hemoglobin alpha Antibody / HBA (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment (within amino acids 1-100) of human HBA2 protein was used as the immunogen for the recombinant Hemoglobin alpha antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant Hemoglobin alpha antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant Hemoglobin alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    HBA1 (Hemoglobin, alpha 1 (HBA1))

    别名

    Hemoglobin alpha

    背景

    Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The alpha and beta globin loci determine the basic Hgb structure. The globin portion of Hgb consists of two alpha chains and two beta chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between alpha and beta chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the alpha1-beta2 cleavage plane. When the two alpha1-beta2 interfaces are closely bound, Hgb has a low affinity for oxygen. Hb A, which contains two alpha chains plus two beta chains, comprises 97 % of total circulating hemoglobin. The remaining 3 % of total circulating hemoglobin is comprised of Hb A-2, which consists of two alpha chains plus two delta chains, and fetal hemoglobin (Hb F), which consists of two alpha chains together with two gamma chains.

    UniProt

    P69905
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