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Recombinant E2F4 抗体 (AA 1-100)

The 兔 单克隆 anti-E2F4 antibody is suitable to detect E2F4 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7867845
发货至: 中国
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Room 801-803
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Quick Overview for Recombinant E2F4 抗体 (AA 1-100) (ABIN7867845)

抗原

See all E2F4 抗体
E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 41
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单克隆

标记

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This E2F4 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

E2F4-8645R
  • 抗原表位

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    AA 1-100

    原理

    E2F4 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-100) from the human protein was used as the immunogen for the E2F4 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the E2F4 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot the E2F4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))

    别名

    E2F4

    背景

    The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcription regulators including E2F-2, E2F-3, E2F-4, E2F-5, E2F-6 and E2F-7 each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.

    UniProt

    Q16254

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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