Recombinant SELPLG 抗体 (PE)
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北京 101111
Quick Overview for Recombinant SELPLG 抗体 (PE) (ABIN7867426)
抗原
See all SELPLG 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE-conjugated Anti-CD162 antibody(DMC283), IgG1 Chimeric mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG1
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应用备注
- Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C-8°C for 6 months
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有效期
- 6 months
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- SELPLG (Selectin P Ligand (SELPLG))
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别名
- SELPLG
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背景
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Synonyms: PSGL-1,PSGL1,CD162,SELPLG,Selectin P ligand
Target Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
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UniProt
- Q14242
抗原
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