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Recombinant MUC16 抗体 (PE)

This 兔 Chimeric antibody specifically detects MUC16 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7867376
发货至: 中国
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Quick Overview for Recombinant MUC16 抗体 (PE) (ABIN7867376)

抗原

See all MUC16 (CA125) 抗体
MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

抗体类型

Recombinant Antibody

适用

  • 155
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宿主

  • 85
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克隆类型

  • 121
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Chimeric

标记

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This MUC16 antibody is conjugated to PE

应用范围

  • 74
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Flow Cytometry (FACS)

克隆位点

3B11
  • 原理

    PE-conjugated Anti-MUC16 antibody(3B11), IgG1 Chimeric mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid PBS with 0.05 %  Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2°C-8°C for 6 months

    有效期

    6 months
  • 抗原

    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

    别名

    MUC16

    背景

    Synonyms: CA125

    Target Background: This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes. [provided by RefSeq, May 2017]

    UniProt

    Q8WXI7
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