Recombinant CCR1 抗体 (PE)
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Quick Overview for Recombinant CCR1 抗体 (PE) (ABIN7867198)
抗原
See all CCR1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE-conjugated Anti-CCR1 antibody(DMC465), IgG1 Chimeric mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG1
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应用备注
- Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C-8°C for 6 months
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有效期
- 6 months
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- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
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别名
- CCR1
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背景
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Synonyms: CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
Target Background: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
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UniProt
- P32246
抗原
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