CD86 抗体 (PE)
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北京 101111
Quick Overview for CD86 抗体 (PE) (ABIN7867187)
抗原
See all CD86 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE-conjugated Anti-B7-2 antibody(DM84), Rabbit mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG
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应用备注
- Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C-8°C for 6 months
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有效期
- 6 months
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- CD86
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别名
- B7-2
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背景
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Synonyms: CD86, B7-2, B70, CD28LG2, LAB72, MGC34413
Target Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
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UniProt
- P42081
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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