Recombinant CD56 抗体
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北京 101111
Quick Overview for Recombinant CD56 抗体 (ABIN7866125)
抗原
See all CD56 (NCAM1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Mouse anti Human CD56
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产品特性
- NCAM / CD56, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM can be found in central and peripheral nerve cells, neuroendocrine tissues and at the surface of NK-cells. Also, NCAM is present in malignancies derived from these tissues and cells.
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纯化方法
- Protein A/G Chromatography
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免疫原
- Mouse monoclonal antibody 0566P is a recombinant CD56 monoclonal antibody produced in mammalian HEK293 cells. It is produced by cloning the antibody sequence of the mouse anti CD56 hybridoma C5.9, which was derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c F1 mice immunized with an extract from the KG1a cell line.
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亚型
- IgG2b
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anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 759-858) antibody
NCAM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) antibodyNCAM1 适用: 人, 小鼠, 猴 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5B1G11 unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (Internal Region) antibodyVerified NCAM1 适用: 人 FACS, WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) antibodyNCAM1 适用: 人, 大鼠 FACS, WB, IHC, IF 宿主: 小鼠 Monoclonal NCAM1-795 unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 568-708) antibodyNCAM1 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 1F6F10 unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) antibody (PerCP)NCAM1 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-188 PerCP
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 701-800) antibodyNCAM1 适用: 人, 大鼠, 小鸡 FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 829-863), (C-Term) antibodyNCAM1 适用: 人 FACS, WB 宿主: 兔 Polyclonal RB51136 unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 796-830), (C-Term) antibodyNCAM1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB51135 unconjugated
anti-Neural Cell Adhesion Molecule 1 (NCAM1) (AA 340-608) antibodyNCAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- 0566P is suitable for flow cytometry, immunocytochemistry, and immunohistochemistry on frozen and paraffin-embedd tissue sections. Optimal antibody dilution should be determined by titration, recommended range is 1:200 - 1:500 for immunohistochemistry with fluorochrome conjugated secondary antibodies or with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent.
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限制
- 仅限研究用
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缓冲液
- Each vial contains 100 µL 1 mg/mL ProtA purified recombinant monoclonal antibody in PBS containing 0.09 % sodium azide. The purity of the antibody is >95 % as determined by SDS-Polyacrylamide gel electrophoresis. The endotoxin level is < 1EU/mg as determined by the LAL chromogenic endotoxin assay.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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别名
- CD56
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背景
- CD56/Neural Cell Adhesion Molecule/NCAM
抗原
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