CD56 抗体
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北京 101111
Quick Overview for CD56 抗体 (ABIN7866124)
抗原
See all CD56 (NCAM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti Human CD56 Prediluted
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产品特性
- NCAM / CD56, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM can be found in central and peripheral nerve cells, neuroendocrine tissues and at the surface of NK-cells. Also, NCAM is present in malignancies derived from these tissues and cells.
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纯化方法
- Protein A/G Chromatography
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免疫原
- Extract from KG1a cell line.,Derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c F1 mice immunized with KG1a cell line.
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亚型
- IgG2b
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应用备注
- Product provided in dropper bottle and should be used as provided. Use 2-3 drops per section or sufficient solution to cover section.
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限制
- 仅限研究用
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缓冲液
- Prediluted monoclonal antibody C5.9 in PBS containing 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Product should be stored at 4-8°C. DO NOT FREEZE
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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别名
- CD56
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背景
- CD56, NCAM, Neural Cell Adhesion Molecule
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UniProt
- P13591
抗原
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