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VCAM1 抗体

This 小鼠 单克隆 antibody specifically detects VCAM1 in FACS, IHC, ICC, ELISA 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7865753
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VCAM1 抗体 (ABIN7865753)

抗原

See all VCAM1 抗体
VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This VCAM1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)

克隆位点

B-K9
  • 原理

    anti-CD106 mouse monoclonal, B-K9, purified

    纯化方法

    affinity chromatography

    免疫原

    activated umbilical cord vein endothelial cells (HUVEC)

    亚型

    IgG1 kappa
  • 应用备注

    ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)

    FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

    IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

    elisa_dilution: assay dependent

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    store at 2 - 8 °C
  • 抗原

    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

    别名

    CD106

    背景

    CD106 is a protein of 110 kDa, also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100. CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. In addition, epithelial cells and cancers cells can be positive, like in kidney and prostate cancer. CD106 serves as a ligand for leukocytes integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. B-K9 inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells. Positive control: Human placenta or tonsil, kidney, some prostate cancers.

    途径

    Carbohydrate Homeostasis
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