Thyroglobulin 抗体
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Quick Overview for Thyroglobulin 抗体 (ABIN7865744)
抗原
See all Thyroglobulin (TG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-Thyroglobulin mouse monoclonal, EBS-O-170, purified
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纯化方法
- affinity chromatography
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免疫原
- human thyroglobulin
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亚型
- IgG1 kappa
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应用备注
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ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)
FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)
WB_dilution: 1:100-1:200 (0.5-1 μg/mL)
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
elisa_dilution: assay dependent
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- Thyroglobulin (TG)
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别名
- Thyroglobulin
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背景
- EBS-O-170 reacts with thyroglobulin, a 660 kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. The vast majority of follicular carcinomas of the thyroid are positive for thyroglobulin even though sometimes only focally. Poorly differentiated thyroid carcinomas are frequently thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. EBS-O-170 has a high affinity for thyroglobulin (Ka = 8.6 x 10^-9). Positive control: Human thyroid.
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途径
- Thyroid Hormone Synthesis
抗原
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