SALL4 抗体
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北京 101111
Quick Overview for SALL4 抗体 (ABIN7865730)
抗原
See all SALL4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-SALL4 mouse monoclonal, IHC659, purified
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纯化方法
- affinity chromatography
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免疫原
- Recombinant Human SALL4
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亚型
- IgG1
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应用备注
- Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- SALL4 (Sal-Like 4 (SALL4))
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别名
- SALL4
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背景
- Sal-Like Protein 4 (SALL4) is a zinc finger transcription factor found in germ cells and human blood progenitor cells, with functional involvement in modulating Oct-4 to maintain embryonic stem cell pluripotency. SALL4 is a useful marker for acute myeloid leukemia, B-cell acute lymphocytic leukemia, intratubular germ cell neoplasia, seminomas/dysgerminomas, and yolk sac tumours (both pediatric and postpubertal). Anti-SALL4 is used to detect embryonal carcinomas, hepatocellular carcinoma (HCC), gliomas, ovarian primitive germcell tumours, choriocarcinomas, spermatogonia, teratoma, gastric cancer, breast cancer, and lung cancer. Expression of SALL4 is often associated with poor prognosis in HCC, and with metastasis in endometrial cancer, colorectal carcinoma, and esophageal squamous cell carcinoma.
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途径
- Stem Cell Maintenance, Tube Formation
抗原
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