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Progesterone Receptor 抗体

This 小鼠 单克隆 antibody specifically detects Progesterone Receptor in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7865720
发货至: 中国
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Quick Overview for Progesterone Receptor 抗体 (ABIN7865720)

抗原

See all Progesterone Receptor (PGR) 抗体
Progesterone Receptor (PGR)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Progesterone Receptor antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

PR-80
  • 原理

    anti-Progesterone Receptor mouse monoclonal, PR-80, purified

    纯化方法

    affinity chromatography

    免疫原

    recombinant human progesterone receptor protein

    亚型

    IgG1 kappa
  • 应用备注

    IHC-paraffin_dilution: 1:25-1:50 (2-4 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)

    IHC-frozen_dilution: 1:25-1:50 (2-4 μg/mL)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    store at 2 - 8 °C
  • 抗原

    Progesterone Receptor (PGR)

    别名

    Progesterone Receptor

    背景

    PR-80 is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect an intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. Positive control: PR positive breast cancer, T47-D cells.

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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