PAX5 抗体
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北京 101111
Quick Overview for PAX5 抗体 (ABIN7865710)
抗原
See all PAX5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-PAX-5 mouse monoclonal, IHC005, purified
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纯化方法
- affinity chromatography
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免疫原
- Recombinant Human PAX-5
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亚型
- IgG1
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应用备注
- Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- PAX5 (Paired Box 5 (PAX5))
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别名
- PAX-5
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背景
- PAX5 is a member of the paired box (PAX) family of transcription factors, which are key regulators in early development. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP), whose expression is limited to early stages of B-cell differentiation. Anti-PAX5 is useful in differentiating between classic Hodgkin's lymphoma versus multiple myeloma and solitary plasmacytoma, as the protein is expressed in mature and precursor B-cell non-Hodgkin's lymphomas/leukemias while being absent from the other two conditions. Diffuse large B-cell lymphomas are positive for PAX5, with the exception of those with terminal B-cell differentiation, and T-cell neoplasms do not stain with Anti-PAX5.
抗原
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