MVP 抗体
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北京 101111
Quick Overview for MVP 抗体 (ABIN7865689)
抗原
See all MVP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-Major vault protein (MVP) mouse monoclonal, 1032, purified
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纯化方法
- affinity chromatography
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免疫原
- affinity purified nuclear extract proteins
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亚型
- IgG1 kappa
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anti-Major Vault Protein (MVP) (AA 1-893) antibody
MVP 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2H3-1A6 unconjugated
anti-Major Vault Protein (MVP) (AA 2-272) antibodyMVP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyKO Validated MVP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) (AA 2-259) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) (AA 88-180) antibodyMVP 适用: 人, 斑马鱼 ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyKD Validated MVP 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB465 unconjugated Recombinant Antibody
anti-Major Vault Protein (MVP) (AA 863-893), (C-Term) antibodyMVP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB02061 unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) (N-Term) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)
IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM Tris with 1 mM EDTA pH 9.0 recommended)
WB_dilution: 1:50-1:100 (1-2 μg/mL)
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- MVP (Major Vault Protein (MVP))
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背景
- 1032 Is specific for the major vault protein, a 104-kDa highly conserved protein interacting with estrogen receptor. It is one of a series of four mAbs which recognize different epitopes of the protein. Major vault proteins have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy. Positive control: MCF-7 or HeLa cells. Breast cancer.
抗原
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