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Integrin Alpha2b 抗体

This 小鼠 单克隆 antibody specifically detects Integrin Alpha2b in FACS, IHC, IF 和 ICC. It exhibits reactivity toward 人.
产品编号 ABIN7865660
发货至: 中国
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Room 801-803
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Quick Overview for Integrin Alpha2b 抗体 (ABIN7865660)

抗原

See all Integrin Alpha2b (CD41) 抗体
Integrin Alpha2b (CD41)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin Alpha2b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

96-2C1
  • 原理

    anti-CD41a mouse monoclonal, 96-2C1, purified

    纯化方法

    affinity chromatography

    免疫原

    stimulated human PBL

    亚型

    IgG1 kappa
  • 应用备注

    ICC/IF_dilution: 1:50-1:100 (1-2 μg/mL)

    FACS_dilution: 1-2 μg/million cells

    IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    store at 2 - 8 °C
  • 抗原

    Integrin Alpha2b (CD41)

    别名

    CD41a

    背景

    96-2C1 reacts with a calcium-dependent complex of CD41/CD61 (GPIIb/IIIa, integrin IIa/3), a dimer of 90 and 140 kDa, present on the membrane of normal platelets and megakaryocytes. This complex forms the receptor of fibrinogen, fibronectin and Von Willebrand factor, and mediates platelet adhesion and aggregation. MAbs to CD41a have been shown to have anti-proliferative effects on various lymphoid cell lines, particularly those derived from large cell lymphomas. 96-2C1 was typed at the IIId HLDA workshop. Positive control: KG1a, HEL cells, and human platelets in lymph nodes or tonsils.

    途径

    Integrin Complex
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