Integrin Alpha2b 抗体
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北京 101111
Quick Overview for Integrin Alpha2b 抗体 (ABIN7865660)
抗原
See all Integrin Alpha2b (CD41) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-CD41a mouse monoclonal, 96-2C1, purified
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纯化方法
- affinity chromatography
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免疫原
- stimulated human PBL
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亚型
- IgG1 kappa
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应用备注
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ICC/IF_dilution: 1:50-1:100 (1-2 μg/mL)
FACS_dilution: 1-2 μg/million cells
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- Integrin Alpha2b (CD41)
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别名
- CD41a
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背景
- 96-2C1 reacts with a calcium-dependent complex of CD41/CD61 (GPIIb/IIIa, integrin IIa/3), a dimer of 90 and 140 kDa, present on the membrane of normal platelets and megakaryocytes. This complex forms the receptor of fibrinogen, fibronectin and Von Willebrand factor, and mediates platelet adhesion and aggregation. MAbs to CD41a have been shown to have anti-proliferative effects on various lymphoid cell lines, particularly those derived from large cell lymphomas. 96-2C1 was typed at the IIId HLDA workshop. Positive control: KG1a, HEL cells, and human platelets in lymph nodes or tonsils.
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途径
- Integrin Complex
抗原
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