ITGAL 抗体
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北京 101111
Quick Overview for ITGAL 抗体 (ABIN7865659)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-CD11a mouse monoclonal, 87-6F9, purified
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纯化方法
- affinity chromatography
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免疫原
- stimulated human leucocytes
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亚型
- IgG2b kappa
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应用备注
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ICC/IF_dilution: assay dependent
FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
WB_dilution: 1:50-1:100 (1-2 μg/mL)
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- CD11a
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背景
- 87-6F9 Reacts with CD11a, a transmembrane molecule with 1145 amino acid residues and a MW of 180 kDa. CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages. Levels on memory T-cells tend to increase. CD11a plays a key role in mediating leukocyte adhesion to endothelium during inflammatory response through binding to ICAM 1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many other T-cell functions and immune phenomena. When paired with CD18, it forms the integrin alphaLbeta2 adhesion. 87-6F9 potently blocks LFA-1 dependent homotypic cell aggregation and was typed in the IVth International Leucocyte Typing Workshop. Positive control: Human leucocytes.
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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