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ITGAL 抗体

The 小鼠 单克隆 anti-ITGAL antibody (Clone 87-6F9) (ABIN7865659) specifically detects ITGAL in FACS, WB, IHC, IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7865659
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ITGAL 抗体 (ABIN7865659)

抗原

See all ITGAL 抗体
ITGAL (Integrin alpha-L (ITGAL))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ITGAL antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

87-6F9
  • 原理

    anti-CD11a mouse monoclonal, 87-6F9, purified

    纯化方法

    affinity chromatography

    免疫原

    stimulated human leucocytes

    亚型

    IgG2b kappa
  • 应用备注

    ICC/IF_dilution: assay dependent

    FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

    WB_dilution: 1:50-1:100 (1-2 μg/mL)

    IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    store at 2 - 8 °C
  • 抗原

    ITGAL (Integrin alpha-L (ITGAL))

    别名

    CD11a

    背景

    87-6F9 Reacts with CD11a, a transmembrane molecule with 1145 amino acid residues and a MW of 180 kDa. CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages. Levels on memory T-cells tend to increase. CD11a plays a key role in mediating leukocyte adhesion to endothelium during inflammatory response through binding to ICAM 1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many other T-cell functions and immune phenomena. When paired with CD18, it forms the integrin alphaLbeta2 adhesion. 87-6F9 potently blocks LFA-1 dependent homotypic cell aggregation and was typed in the IVth International Leucocyte Typing Workshop. Positive control: Human leucocytes.

    途径

    Activated T Cell Proliferation, Integrin Complex
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