CCL16 抗体
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北京 101111
Quick Overview for CCL16 抗体 (ABIN7865613)
抗原
See all CCL16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-LEC / CCL16 / HCC4 mouse monoclonal, LEC-14, purified
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纯化方法
- affinity chromatography
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免疫原
- recombinant human LEC
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亚型
- IgG1 kappa
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应用备注
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IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
elisa_dilution: assay dependent
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
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别名
- LEC / CCL16 / HCC4
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背景
- Liver Expressed Chemokine (LEC) is an 11 kDa inflammation related agent, known under many synonyms like Chemokine (C-C motif) Ligand 16 (CCL16), HCC4, NCC4, Monotactin-1 (MTN-1) etc. It is preferentially expressed and secreted by liver cells, but also found in spleen and thymus. It shows chemotactic activity towards activated lymphocytes and monocytes but not to neutrophils or resting lymphocytes. In monocytes, it is highly expressed after IL-10, LPS or IFN-gamma induction. It also shows potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. LEC-receptors include CCR1, CCR2, CCR5 and CCR8. It is present in human serum in which it can be measured by ELISA. Positive control: Liver, spleen and thymus.
抗原
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