beta-2 Microglobulin 抗体
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Quick Overview for beta-2 Microglobulin 抗体 (ABIN7865565)
抗原
See all beta-2 Microglobulin (B2M) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-Beta-2-microglobulin mouse monoclonal, EBS-O-109, purified
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交叉反应 (详细)
- not with non human primates
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纯化方法
- affinity chromatography
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免疫原
- human PBL from a T-ALL patient
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亚型
- IgG2a kappa
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应用备注
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FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
elisa_dilution: assay dependent
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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别名
- Beta-2-microglobulin
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背景
- EBS-O-109 reacts with human β-2 microglobulin, a 22 kDa protein, which associates non-covalently with the 44 kDa α1-chain of the HLA Class I complex found on all nucleated cells and on platelets. There is no reaction with erythrocytes, neither with non-human primate cells. The detection of β-2 microglobulin in body fluids has been used as a tumor marker, renal failure marker and for monitoring patients with HIV infection. Positive control: Human PBL.
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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