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Ubiquitin 抗体

The 兔 多克隆 anti-Ubiquitin antibody is suitable to detect Ubiquitin in samples from 人, 大鼠 和 小鼠. It has been validated for IHC, ELISA 和 IF.
产品编号 ABIN7862565
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Ubiquitin 抗体 (ABIN7862565)

抗原

See all Ubiquitin (Ub) 抗体
Ubiquitin (Ub)

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Ubiquitin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 原理

    Rabbit Anti-Ub Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of Ub

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human Ub protein at AA range: 1-50

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Ubiquitin (Ub)

    别名

    Ub

    背景

    Polyubiquitin-B, UBBUBB encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. UBB consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of UBB are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

    基因ID

    7314

    UniProt

    P0CG47, P0CG48, P62979, P62987

    途径

    Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
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