OPRL1 抗体
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北京 101111
Quick Overview for OPRL1 抗体 (ABIN7862541)
抗原
See all OPRL1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-OPRX Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of OPRX protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human OPRX protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- OPRL1 (Opiate Receptor-Like 1 (OPRL1))
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别名
- OPRX
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背景
- Nociceptin receptor, Kappa-type 3 opioid receptor, KOR-3, Orphanin FQ receptorThe protein encoded by OPRL1 is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between OPRL1 and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for OPRL1. A recent study provided evidence for translational readthrough in OPRL1 and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
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分子量
- 40kD
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基因ID
- 4987
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UniProt
- P41146
抗原
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