Obestatin 抗体
The 兔 多克隆 anti-Obestatin antibody (ABIN7862539) specifically detects Obestatin in ELISA, IHC 和 IF.
The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7862539
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Obestatin 抗体 (ABIN7862539)
抗原
See all Obestatin (OB) 抗体
Obestatin (OB)
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This Obestatin antibody is un-conjugated
应用范围
ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
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原理
- Rabbit Anti-Ob Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of Ob
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human Ob protein at AA range: 10-50
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亚型
- IgG
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anti-Obestatin (OB) (AA 76-98) antibody
OB 适用: 人, 小鼠 ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Obestatin (OB)
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别名
- Ob
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背景
- Leptin, Obese protein, Obesity factorLEP encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations inLEP and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in LEP has also been linked to type 2 diabetes mellitus development. LEP (Leptin) is a Protein Coding gene. Diseases associated with LEP include Obesity, Morbid, Due To Leptin Deficiency and Obesity Due To Congenital Leptin Deficiency. Among its related pathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and Transcription factor regulation in adipogenesis.
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基因ID
- 3952
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UniProt
- P41159
抗原
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