GR (Ser211) 抗体
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北京 101111
Quick Overview for GR (Ser211) 抗体 (ABIN7862531)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser211
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原理
- Rabbit Anti-GR Polyclonal Antibody
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特异性
- GR Polyclonal Antibody detects endogenous levels of GR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human GR around the non-phosphorylation site of S211
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亚型
- IgG
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anti-GR (AA 20-199) antibody
适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GR (Internal Region), (pSer211) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-GR (AA 150-200) antibody适用: 人 WB, IHC, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-GR (pSer203) antibody适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-GR (AA 181-230) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GR (AA 201-250), (pSer226) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GR (AA 1-50) antibody适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-GR (pSer211) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GR (pSer226) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GR (AA 181-230), (pSer211) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- GR
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背景
- NR3C1, GRL, Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1NR3C1 encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in NR3C1 are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID: 15866175).
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分子量
- 95kD
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基因ID
- 2908
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UniProt
- P04150
抗原
-
