PKA 抗体 (pSer338)
The 兔 多克隆 anti-PKA antibody is suitable to detect PKA in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA, IF 和 IHC.
产品编号 ABIN7862487
发货至:
中国
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Contact Info
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中国
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Quick Overview for PKA 抗体 (pSer338) (ABIN7862487)
抗原
See all PKA 抗体
PKA
(Protein Kinase A (PKA))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This PKA antibody is un-conjugated
应用范围
ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
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抗原表位
- pSer338
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原理
- Rabbit Anti-PKAα cat (phospho Ser338) Polyclonal Antibody
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特异性
- Phospho-PKAα cat (S338) Polyclonal Antibody detects endogenous levels of PKAα cat protein only when phosphorylated at S338.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human PKAalpha cat Phospho-Ser338
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亚型
- IgG
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anti-Protein Kinase A (PKA) (AA 17-100) antibody
PKA 适用: 人, 小鼠 WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A (PKA) (Catalytic Subunit) antibodyPKA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- PKA (Protein Kinase A (PKA))
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别名
- PKAα
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背景
- PRKACA, PKACA, cAMP-dependent protein kinase catalytic subunit alpha, PKA C-alphaPRKACA (protein kinase cAMP-activated catalytic subunit alpha) encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms.
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基因ID
- 5566
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UniProt
- P17612
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途径
- SARS-CoV-2 Protein Interactome
抗原
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