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PR (pSer294) 抗体

This 兔 多克隆 antibody specifically detects PR in WB 和 IHC. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7862486
发货至: 中国
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Quick Overview for PR (pSer294) 抗体 (ABIN7862486)

抗原

PR

适用

  • 12
  • 5
  • 4
  • 2
  • 1
人, 大鼠, 小鼠

宿主

  • 10
  • 2

克隆类型

  • 9
  • 3
多克隆

标记

  • 12
非结合性

应用范围

  • 11
  • 8
  • 8
  • 7
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pSer294

    原理

    Rabbit Anti-PR (phospho Ser294) Polyclonal Antibody

    特异性

    Phospho-PR (S294) Polyclonal Antibody detects endogenous levels of PR protein only when phosphorylated at S294.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human PR Phospho-Ser294

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PR

    背景

    PGR, NR3C3, Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3PGR (progesterone receptor) encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

    分子量

    98kD

    基因ID

    5241

    UniProt

    P06401
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