Ubiquitin 抗体 (acLys27)
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Quick Overview for Ubiquitin 抗体 (acLys27) (ABIN7862469)
抗原
See all Ubiquitin (Ub) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys27
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原理
- Rabbit Anti-Ub (Acetyl Lys27) Polyclonal Antibody
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特异性
- Acetyl-Ub (K27) Polyclonal AntibodySynthesized peptide derived from the human Ub around the acetylation site of K27.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the human Ub around the acetylation site of K27
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亚型
- IgG
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anti-Ubiquitin (Ub) antibody
Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin (Ub) (AA 1-229) antibodyUb 适用: 人, 大鼠, 小鼠, Cow, Pig, 犬, 马, 兔 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin (Ub) (AA 1-229) antibodyUb 适用: 人, 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Ubiquitin (Ub) (acLys27) antibodyUb 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin (Ub) antibody (Atto 390)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 390
anti-Ubiquitin (Ub) antibody (Atto 488)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 488
anti-Ubiquitin (Ub) antibody (Atto 594)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Atto 594
anti-Ubiquitin (Ub) antibody (APC)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal APC
anti-Ubiquitin (Ub) antibody (Biotin)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal Biotin
anti-Ubiquitin (Ub) antibody (FITC)Ub 适用: Cow WB, IHC, ICC, IF, IP 宿主: 兔 Polyclonal FITC
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Ubiquitin (Ub)
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别名
- Ub
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背景
- UBB, Polyubiquitin-B, UBC, Polyubiquitin-C, RPS27A, UBA80, UBCEP1, Ubiquitin-40S ribosomal protein S27a, Ubiquitin carboxyl extension protein 80, UBA52, UBCEP2, Ubiquitin-60S ribosomal protein L40, CEP52, Ubiquitin A-52 residue ribosomal protein fusion prUbiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of ubiquitin is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. This small, 76 amino acid protein can be covalently attached to cellular proteins via an isopeptide linkage between the carboxy terminal group of ubiquitin and lysine amino groups on the acceptor protein. For proteolysis to occur, ubiquitin oligomers must be assembled. Ubiquitin chains on proteolytic substrates are commonly found to have an isopeptide bridge between Lysine 48 of one ubiquitin molecule and the carboxy-terminus of a neighboring ubiquitin molecule. Ubiquitin also plays a role in regulating signal transduction cascades through the elimination inhibitory proteins, such as IκBα and p27.
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UniProt
- P62987, P62979, P0CG47, P0CG48
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途径
- Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
抗原
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