FX (AA 190-270) 抗体
Our Local Distributor
北京 101111
Quick Overview for FX (AA 190-270) 抗体 (ABIN7862458)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 190-270
-
原理
- Rabbit Anti-FX Polyclonal Antibody
-
特异性
- FX Polyclonal Antibody detects endogenous levels of FX protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from the C-terminal region of human FX at AA range: 190-270
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- FX
-
背景
- TSTA3, SDR4E1, GDP-L-fucose synthase, GDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase, Protein FX, Red cell NADP(H)-binding protein, Short-chain dehydrogenase/reductase family 4E member 1Tissue specific transplantation antigen P35B is a NADP (H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in TSTA3 (tissue specific transplantation antigen P35B)may cause leukocyte adhesion deficiency, type II.
-
分子量
- 40kD
-
基因ID
- 7264
-
UniProt
- Q13630
抗原
-