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Recombinant S100B 抗体

The 兔 单克隆 anti-S100B antibody (Clone MSVA-490R) (ABIN7865526) specifically detects S100B in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7865526
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Recombinant S100B 抗体 (ABIN7865526)

抗原

See all S100B 抗体
S100B (S100 Calcium Binding Protein B (S100B))

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This S100B antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

MSVA-490R
  • Expression System

    HEK-293 Cells

    原理

    Recombinant S100B (Astrocyte and Melanoma Marker) Antibody

    特异性

    S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.

    纯化方法

    Ab produced in HEK293 cell mammalian-based expression system.

    免疫原

    Recombinant full-length human S100B protein

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    S100B (S100 Calcium Binding Protein B (S100B))

    别名

    S100B

    背景

    NEF, Protein S100-B, S-100 protein beta chain, S100 calcium binding protein beta (neural), S100 calcium-binding protein B, S100 protein beta chain, S100B, S100beta

    Appendix: Schwann cells of peripheral nerves and adipocytes should show a strong, predominantly cytoplasmic S100B staining.

    分子量

    10-12kDa

    基因ID

    6285, 422181

    UniProt

    P04271

    途径

    Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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