Recombinant Elastin 抗体
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Quick Overview for Recombinant Elastin 抗体 (ABIN7865516)
抗原
See all Elastin (ELN) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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Expression System
- HEK-293 Cells
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原理
- Recombinant Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody
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特异性
- Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
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纯化方法
- Ab produced in HEK293 cell mammalian-based expression system.
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免疫原
- Recombinant full-length human Elastin protein
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亚型
- IgG, kappa
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anti-Elastin (ELN) (AA 681-786) antibody
ELN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Elastin (ELN) (AA 392-645) antibodyELN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastin (ELN) (AA 266-443) antibodyELN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastin (ELN) antibodyELN 适用: 人 IHC, ELISA, IHC (p), IF, RIA 宿主: 兔 Polyclonal unconjugated
anti-Elastin (ELN) antibodyELN 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal ELN-1981 unconjugated
anti-Elastin (ELN) antibodyELN 适用: 人 IHC 宿主: 兔 Monoclonal ELN-3131R unconjugated Recombinant Antibody
anti-Elastin (ELN) (full length) antibodyELN 适用: 人 IHC 宿主: 兔 Monoclonal 648R unconjugated Recombinant Antibody
anti-Elastin (ELN) (AA 392-645) antibodyELN 适用: 人 WB 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Elastin (ELN) antibodyELN 适用: 人, 小鼠, Cow, 小鸡 WB, IHC, IP, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 10B8 unconjugated
anti-Elastin (ELN) (AA 27-200) antibodyELN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Elastin (ELN)
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别名
- Elastin
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背景
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Elastin, ELN, SVAS, Tropoelastin, WBS, WS
Colon: A moderate to strong elastin immunostaining should be seen of fibres in the lamina propria, around smooth muscle cells of the muscularis mucosae, and in blood vessels (subendothelial).
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分子量
- 70kDa
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基因ID
- 2006, 647061
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UniProt
- P15502
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途径
- Regulation of Actin Filament Polymerization
抗原
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