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Recombinant CNN1 抗体 (AA 197-297)

The 小鼠 单克隆 anti-CNN1 antibody is suitable to detect CNN1 in samples from 人. It has been validated for IHC 和 WB.
产品编号 ABIN7862409
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CNN1 抗体 (AA 197-297) (ABIN7862409)

抗原

See all CNN1 抗体
CNN1 (Calponin 1 (CNN1))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CNN1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB)

克隆位点

RCNN1-6918
  • 抗原表位

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    AA 197-297

    原理

    Recombinant Calponin-1 (Smooth Muscle Marker) Antibody

    特异性

    Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

    纯化方法

    200ug/ml of recombinant MAb purified by Protein A/G.

    免疫原

    Recombinant fragment (around aa197-297) of human CNN1 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    CNN1 (Calponin 1 (CNN1))

    别名

    Calponin-1

    背景

    Calponin 1 basic smooth muscle, Calponin H1 smooth muscle, Calponin-1, CNN1, Cnn1, Sm Calp, SMCC

    K562 cells or Colon. Myoepithelial cells in breast ducts.

    分子量

    34kDa

    基因ID

    1264, 465929
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