Recombinant beta Amyloid 抗体 (AA 500-700)
Our Local Distributor
北京 101111
Quick Overview for Recombinant beta Amyloid 抗体 (AA 500-700) (ABIN7862388)
抗原
See all beta Amyloid (Abeta) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 500-700
-
原理
- Recombinant beta Amyloid Antibody
-
特异性
- Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the ≤-Amyloid and Amyloid A4 proteins, which are present in human platelets. Amyloid deposition is associated with type II diabetes, Down syndrome and a variety of neurological disorders, including Alzheimer s disease. The Amyloid precursor protein (APP) undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the 4 kDa Amyloid ≤/A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.
-
纯化方法
- 200ug/ml of Ab purified from rabbit anti-serum by Protein A.
-
免疫原
- Recombinant fragment (around aa500-700) of human APP protein (exact sequence is proprietary)
-
亚型
- IgG, kappa
-
-
anti-Amyloid beta (Abeta) (C-Term) antibody
Abeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 9E8-1A3 unconjugated
anti-Amyloid beta (Abeta) (AA 711-760) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) antibodyAbeta 适用: 人 WB, ELISA, IHC, IP, IEM 宿主: 兔 Chimeric 6E10 unconjugated Recombinant Antibody
anti-Amyloid beta (Abeta) (Ser15) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) (pThr743) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
-
别名
- beta Amyloid
-
背景
-
CVAP, AAA, AICD-50, PN2, 50, Beta-APP42, AID, S-APP-alpha, 57, AD1, PN-II, Beta-APP40, 42, 40, APPI, Alzheimer disease amyloid protein, PreA4, ABETA, Amyloid intracellular domain 50, 57, 59 AICD-59, S-APP-beta, APP, AICD-57, ABPP, Protease nexin-II, Cerebral vascular amyloid peptide
Alzheimer's disease brain. Amyloidosis. Brain, U87
-
分子量
- 4-46kDa (é≤-Amyloid), 100-125kDa (Amyloid A4)
-
基因ID
- 351, 434980
-
UniProt
- P05067
-
途径
- Inflammasome
抗原
-
