Recombinant FLI1 抗体 (AA 200-400)
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Quick Overview for Recombinant FLI1 抗体 (AA 200-400) (ABIN7862359)
抗原
See all FLI1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-400
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原理
- Recombinant FLI1 (Ewing s Sarcoma & Endothelial Marker) Antibody
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特异性
- Recognizes a protein of 51 kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing s Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi s Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.
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纯化方法
- 200ug/ml of Ab purified from rabbit anti-serum by Protein A.
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免疫原
- Recombinant fragment (around aa200-400) of human FLI1 protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 303-452) antibody
FLI1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4F2A9 unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 1-452) antibodyFLI1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 1-452) antibodyFLI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 205-331) antibodyFLI1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 54-73), (N-Term) antibodyFLI1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (N-Term) antibodyFLI1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (Internal Region) antibodyFLI1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (Internal Region) antibodyFLI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) antibodyKD Validated FLI1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2875 unconjugated Recombinant Antibody
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 1-452) antibodyFLI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- FLI1 (Friend Leukemia Virus Integration 1 (FLI1))
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别名
- FLI1
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背景
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ERGB transcription factor, Ewing Sarcoma breakpoint region 2 (EWSR2), FLI1, FLI1 EWS fusion gene, Friend leukemia integration 1 (FLI1) transcription factor, Friend leukemia virus integration 1, Proto-oncogene Fli-1, SIC1, Transcription factor ERGB, Viral integration region FLI1
Ewing s sarcoma (EWS) or angiosarcoma.|THP1 or Raji cells. Human tonsil, Ramos
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分子量
- 51kDa
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基因ID
- 2313, 504281
抗原
-
