FLI1 抗体 (AA 107-261)
Our Local Distributor
北京 101111
Quick Overview for FLI1 抗体 (AA 107-261) (ABIN7862826)
抗原
See all FLI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 107-261
-
原理
- FLI1 (Ewing's Sarcoma & Endothelial Marker) Antibody
-
特异性
- Recognizes a protein of 51 kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing's Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi's Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.
-
纯化方法
- 200ug/ml of Ab purified from rabbit anti-serum by Protein A.
-
免疫原
- Recombinant fragment (aa 107-261) of human FLI1 protein with hexa-histidine tag
-
亚型
- IgG1, kappa
-
-
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 303-452) antibody
FLI1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4F2A9 unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 1-452) antibodyFLI1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 1-452) antibodyFLI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 205-331) antibodyFLI1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 54-73), (N-Term) antibodyFLI1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (N-Term) antibodyFLI1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (Internal Region) antibodyFLI1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (Internal Region) antibodyFLI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) antibodyKD Validated FLI1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2875 unconjugated Recombinant Antibody
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 1-452) antibodyFLI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- FLI1 (Friend Leukemia Virus Integration 1 (FLI1))
-
别名
- FLI1
-
背景
-
ERGB transcription factor; Ewing Sarcoma breakpoint region 2 (EWSR2); FLI1; FLI1 EWS fusion gene; Friend leukemia integration 1 (FLI1) transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; SIC1; Transcription factor ERGB; Viral integration region FLI1
Ewing's sarcoma (EWS) and Angiosarcoma, THP1 and Raji cells. Tonsil
-
分子量
- 51kDa
-
基因ID
- 2313, 504281
-
UniProt
- Q01543
抗原
-
