S100A8/A9 Complex (Calprotectin) 抗体
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Quick Overview for S100A8/A9 Complex (Calprotectin) 抗体 (ABIN7863363)
抗原
See all S100A8/A9 Complex (Calprotectin) (S100A8/A9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Calprotectin / MRP14 / S100A9 / Calgranulin B Antibody
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特异性
- Recognizes a protein of14 kDa, identified as MRP-14 (also known as Calgranulin B or S100AA9). It comprises 60 % of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. It is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore, it is also detectable in feces. Elevated levels have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions. This MAb reacts with neutrophils, monocytes, and macrophages, and has been shown as an important marker for identifying macrophages in tissue sections.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate.
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免疫原
- Recombinant human MRP14 protein
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亚型
- IgM, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))
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别名
- Calprotectin
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背景
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S100-A9, MRP14, calgranulin-B, calprotectin L1H subunit, leukocyte L1 complex heavy chain, migration inhibitory factor-related protein 14, S100 calcium-binding protein A9 (calgranulin B)
lymph node, or spleen, Tonsil
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分子量
- 14kDa
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基因ID
- 6280
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UniProt
- P06702
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途径
- S100 Proteins
抗原
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