ZBTB46 抗体
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北京 101111
Quick Overview for ZBTB46 抗体 (ABIN7862668)
抗原
See all ZBTB46 (ZNF340) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ZBTB46 / BTBD4 / ZNF340 Antibody
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特异性
- BTBD4 (BTB/POZ domain-containing protein 4), also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46), is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human ZBTB46 protein
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))
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别名
- ZBTB46
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背景
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BTB/POZ domain containing protein 4, BTBD4, RINZF, Zinc finger and BTB domain containing protein 46, Zinc finger protein 340, ZNF340
brain or rectum. HeLa or U-2 OS cells., Human tonsil
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分子量
- 64kDa
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基因ID
- 140685, 585028
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UniProt
- Q86UZ6
抗原
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