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ZNF202 抗体

The 小鼠 单克隆 anti-ZNF202 antibody is suitable to detect ZNF202 in samples from 人. It has been validated for FACS.
产品编号 ABIN7862289
发货至: 中国
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Quick Overview for ZNF202 抗体 (ABIN7862289)

抗原

See all ZNF202 抗体
ZNF202 (Zinc Finger Protein 202 (ZNF202))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ZNF202 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

PCRP-ZNF202-1C4
  • 原理

    ZNF202 Antibody

    特异性

    Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF202 (zinc finger protein 202), also known as ZKSCAN10, is a 648 amino acid protein that contains eight C2H2-type zinc fingers, one KRAB domain and one SCAN box domain. Localized to the nucleus and expressed at high levels in the testis, ZNF202 belongs to the Kruppel C2H2-type zincfinger protein family and functions as a transcriptional repressor of genes that are involved in lipid metabolism. ZNF202 regulates the expression of several classes of proteins, including lipoprotein particles, transporters involved in lipid homeostasis, enzymes involved in lipid processing and a wide variety of proteins that are associated with energy metabolism. Defects in the gene encoding ZNF202 are associated with high cholesterol and may be involved in the pathogenesis of lung, ovarian and breast cancer. Two isoforms of ZNF202, designated a and b, exist due to alternative splicing events

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around 37-132) of human ZNF202 protein

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    ZNF202 (Zinc Finger Protein 202 (ZNF202))

    别名

    ZNF202

    背景

    ZKSCAN10, ZSCAN42

    HeLa or MCF-7 cells.

    分子量

    74.72kDa

    基因ID

    7753, 112556

    UniProt

    O95125
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