UCHL1 抗体
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北京 101111
Quick Overview for UCHL1 抗体 (ABIN7863489)
抗原
See all UCHL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PGP9.5 / UchL1 (pan-Neuronal Marker) Antibody
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特异性
- This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- KLH conjugated synthetic peptide selected from the 185-214 region of human UCHL1
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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别名
- PGP9.5
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背景
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Gracile Axonal Dystrophy, Neuron Cytoplasmic Park5, Parkinson Disease 5, Protein Gene Product 9.5, Ubiquitin Carboxyl-terminal Esterase L1, Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1, Ubiquitin Thioesterase L1
T98G cells. Cerebellum. Human Brain, Mouse Brain, Rat Brain, Hamster Brain or Guinea pig Brain tissue
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分子量
- 20-30kDa
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基因ID
- 7345, 518731
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UniProt
- P09936
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途径
- Feeding Behaviour
抗原
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