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Recombinant Ubiquitin 抗体

The 小鼠 单克隆 anti-Ubiquitin antibody (Clone rFPM1) (ABIN7865473) specifically detects Ubiquitin in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7865473
发货至: 中国
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北京 101111
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Quick Overview for Recombinant Ubiquitin 抗体 (ABIN7865473)

抗原

See all Ubiquitin (Ub) 抗体
Ubiquitin (Ub)

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Ubiquitin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

RFPM1
  • 原理

    Recombinant Ubiquitin (Autophagy Marker) Antibody

    特异性

    Ubiquitin, a small protein consisting of 76 amino acids, has been found in all eukaryotic cells studied. It is one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation, which eliminates most intracellular defective proteins as well as normal proteins with a rapid turnover. Degradation involves covalent binding of ubiquitin to the protein to be degraded and it is believed that in this way ubiquitin acts to label the protein for disposal by intracellular proteases. The most abundant ubiquitin-protein conjugate, however, is ubiquitin-histone H2A. This conjugate is not degraded. Since such ubiquitinated histones are present primarily in actively transcribed chromosomal regions, ubiquitin may play a role in regulation of gene expression.

    纯化方法

    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Ubiquitin conjugated with glutaraldehyde crosslinked to keyhole limpet hemocyanin (KLH).

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Ubiquitin (Ub)

    别名

    Ubiquitin

    背景

    Epididymis secretory protein Li 50, Polyubiquitin B, RPS27A, UBA52, UBA80, UBB, UBC, UBCEP1, UBCEP2, Ubiquitin, Ubiquitin B

    HeLa or Raji cells. Human brain.

    分子量

    9kDa

    基因ID

    7314, 356190, 520348

    UniProt

    P0CG47

    途径

    Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
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