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TRIM24 抗体

The 小鼠 单克隆 anti-TRIM24 antibody is suitable to detect TRIM24 in samples from 人. It has been validated for IF 和 FACS.
产品编号 ABIN7863566
发货至: 中国
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Room 801-803
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Quick Overview for TRIM24 抗体 (ABIN7863566)

抗原

See all TRIM24 抗体
TRIM24 (Tripartite Motif Containing 24 (TRIM24))

适用

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宿主

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小鼠

克隆类型

  • 55
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单克隆

标记

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This TRIM24 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-TRIM24-1B12
  • 原理

    TRIM24 / TIF1 alpha Antibody

    特异性

    TIF1°™, also known as TRIM24, mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. TIF1°™ localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. TIF1°™ is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. The TIF1°™ gene, which maps to human chromosome 7q33, encodes two alternatively spliced transcripts. However, the full length nature of one variant has not been determined. A TIF1°™ homolog (designated bonus) has been identified in Drosophila and is associated with several genes that are implicated in the ecdysone pathway, a nuclear hormone receptor pathway required throughout Drosophila development, suggesting a conserved functional role for the protein throughout the course of evolution.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human TRIM24 protein

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    TRIM24 (Tripartite Motif Containing 24 (TRIM24))

    别名

    TRIM24

    背景

    E3 ubiquitin protein ligase TRIM24, hTIF1, PTC6, RING finger protein 82, RNF82, TF1A, TIF1 alpha, Transcriptional intermediary factor 1 alpha, Tripartite motif-containing protein 24

    HeLa or K562 cells.

    分子量

    117kDa

    基因ID

    8805, 490287

    UniProt

    O15164
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