TOP1MT 抗体
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北京 101111
Quick Overview for TOP1MT 抗体 (ABIN7862631)
抗原
See all TOP1MT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Topoisomerase (DNA) I, Mitochondrial (TOP1MT) Antibody
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特异性
- DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human TOP1MT protein
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亚型
- IgG2b, kappa
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anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) antibody
TOP1MT 适用: 人 IHC, WB, IF, FACS 宿主: 小鼠 Monoclonal TOP1MT-488 unconjugated
anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (AA 470-550) antibodyTOP1MT 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) antibodyTOP1MT 适用: 人 IHC 宿主: 小鼠 Monoclonal TOP1MT-568 unconjugated
anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) antibodyTOP1MT 适用: 人 IHC 宿主: 兔 Monoclonal TOP1MT-2883R unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) antibodyTOP1MT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (AA 270-400) antibodyTOP1MT 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (Internal Region) antibodyTOP1MT 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (AA 11-238) antibodyTOP1MT 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) (AA 1-238) antibodyTOP1MT 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
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别名
- Topoisomerase I, Mitochondrial
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背景
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DNA topoisomerase I, TOP1MT, Topoisomerase I mitochondrial, Type IB Topoisomerase
A431 cells. Heart, brain or fetal liver., Skeletal muscle
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分子量
- 70kDa
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基因ID
- 116447, 528574
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UniProt
- Q969P6
抗原
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